Jul 11, 2009

Medicinal Mushroom Hot Water Extract vs. Alcohol Extract

By Dr. Markho Rafael

For two millennia, medicinal mushrooms have been mainstream in Asia. Now, America is taking notice and interest is rapidly "mushrooming." With the sprouting of this new industry follows issues of ethical quality claims between competing brands.

This information applies to all species of medicinal mushrooms. For practical purposes, this article will focus on the most popular medicinal mushroom species, red reishi (Ganoderma lucidum), over which the most intense battle of conflicting claims is being fought.

The first and perhaps obvious caution is to stay away from cheap mass-produced brands of medicinal mushrooms that may only contain dried and pulverized mushrooms, in which case the medicinal compounds are still inaccessible behind the mushrooms' cell walls.

There are many real therapeutic brands on the market, though. But even among them, there are significant differences. They all claim to be the best, naturally, because they all want to sell their particular brand. So let's sift the data, get the facts straight, and clear up misleading information that is out there.

Below are three common methods for extracting medicinal compounds from reishi. Each method results in different compounds. All groups have been shown to have therapeutic effects in scientific studies.

1. Water Extraction, Hot (polysaccharides and more)

2. Alcohol Extraction (triterpenoids, etc.)

3. Fermenting (arabinoxylanes, etc.)

The water soluble compounds, primarily polysaccharides, are powerful anti-tumor agents, immune enhancers and strong antioxidants. [1]

The alcohol soluble compounds are mainly triterpenoids, a large group of related compounds. Scientific studies suggest they help stabilize cholesterol, blood pressure and clotting. Most importantly, they are the anti-inflammatory compounds so critical to many of reishi's suggested uses, including arthritis, allergies and asthma. [1]

Less researched are the "secondary metabolites" that come from fermenting reishi. "Secondary" because they result when the original medicinal compounds get broken down by bacteria. These new compounds have been shown to possess therapeutic properties that are unique, including immune enhancement, anti-tumor and blood-sugar regulation. [2]

This article is intended to give general guidelines to help you choose an effective reishi product, not to recommend any particular brand. But there are at least two reishi companies on the market which both state only hot water extract is useful while alcohol extracts are of no value.

They do that, of course, because they wish to sell their products. However, there is no scientific validity to those claims. All three extraction methods listed above yield important medicinal compounds.

To determine if a brand of reishi (or Ganoderma) contains all the important medicinal compounds from the mushroom, find out if it utilizes both alcohol and hot water extraction. An additional plus would be if it also includes fermented reishi.

An additional point to keep in mind is the form the reishi comes in. Reishi that dissolves completely in a water-based liquid such as coffee probably only contains reishi from hot water extraction. As a substitute for regular coffee, this would be a superb health-choice. However, it will not contain the water-insoluble triterpenoids so valued for their anti-inflammatory properties.

Surprisingly, though, alcohol tinctures may include both hot water extract and alcohol extract. You will know if the alcohol tincture contains polysaccharides because when the alcohol and hot water extracts are blended, the polysaccharides fall out of solution and the tincture becomes cloudy. (Just shake it before you take it.) A cloudy medicinal mushroom tincture is an indication of high polysaccharide content. Capsules and tablets may be either hot water extract or alcohol extract or both.

[1] Boh B, Berovic M, Zhang J, Zhi-Bin L. "Ganoderma lucidum and its pharmaceutically active compounds." Biotechnol Annu Rev. 2007;13:265-301.

[2] Tang YJ, Zhang W, Zhong JJ, 2009. "Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum." Bioresource Technol. Mar;100(5):1852-9.

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